Common use

Isentress (raltegravir) is prescribed for the treatment of HIV-1 infection in combination with other antiretroviral medications. It works as an integrase inhibitor, blocking the enzyme HIV integrase, which is necessary for viral replication, helping to control the infection and maintain immune function.

Dosage and direction

Isentress is taken orally, usually twice daily, with or without food. Tablets or chewable formulations should be swallowed whole (or chewed if appropriate). The dosage may vary depending on other antiretroviral medications, kidney function, and patient response. Follow your healthcare provider’s instructions carefully.

Precautions

Inform your doctor if you have liver or kidney disease, a history of muscle disorders, or any allergies. Monitor for signs of muscle pain, weakness, or dark urine. Do not stop taking Isentress without consulting your healthcare provider, as this can lead to viral resistance.

Contraindications

Do not use Isentress if allergic to raltegravir or any component of the tablet. Caution is advised in patients with severe liver disease or concurrent medications that may interact.

Possible side effect

Common side effects include headache, nausea, diarrhea, fatigue, and insomnia. Serious side effects may include severe allergic reactions, liver problems, or muscle breakdown (rhabdomyolysis). Seek medical attention if serious symptoms occur.

Drug interaction

Isentress may interact with certain antacids, rifampin, anticonvulsants, or other medications affecting liver enzymes. Inform your healthcare provider about all prescription drugs, over-the-counter products, and supplements you are taking.

Missed dose

If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose.

Overdose

Overdose may cause nausea, vomiting, or other side effects. Seek immediate medical attention if an overdose is suspected.

Storage

Store Isentress at room temperature, away from moisture, heat, and light. Keep tablets in the original container and out of reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.