What is the most important information I should know about Mobic?

Contact your doctor if you experience bloody, black or tarry stools, blood in your vomit; swelling or rapid weight gain (fluid retention); unusual fatigue or weakness; yellowing of the skin or eyes; excessive itching; flu-like symptoms; or abdominal pain or tenderness. These symptoms could indicate serious side effects.

Many over-the-counter cough, cold, allergy and pain medicines contain aspirin or other medicines similar to Mobic (such as ibuprofen, ketoprofen and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, Mobic may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking Mobic if you drink more than 3 alcoholic beverages a day.

What is Mobic?

Mobic is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Mobic works by reducing hormones that cause inflammation and pain in the body.

Mobic is used to reduce the pain, inflammation and stiffness caused by osteoarthritis and rheumatoid arthritis …

Mobic may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking Mobic?

Before taking this medication, tell your doctor if you

have an allergy to aspirin or any other NSAIDs,

have an ulcer or bleeding in your stomach,

drink more than three alcoholic beverages a day,

have liver disease;

have kidney disease;

have a bleeding or blood clotting disorder,

have congestive heart failure,

have fluid retention,

have heart disease or

have high blood pressure.

You may not be able to take Mobic or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Mobic is in the FDA pregnancy category C. This means it is not known whether Mobic will be harmful to an unborn baby. Mobic should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take Mobic without talking to your doctor first if you are pregnant or could become pregnant during treatment.

Do not take this medication without talking to your doctor first if you are breast-feeding a baby. It is not known whether Mobic passes into breast milk.

How should I take Mobic?

Take Mobic exactly as directed. If you do not understand these instructions, ask your pharmacist, nurse or doctor to explain them to you.

Each dose should be taken with a full glass of water.

Mobic may be taken with or without food.

Store Mobic at room temperature away from moisture and heat.

What happens if I miss a dose?

If you are taking Mobic on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.

If you are taking Mobic as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a Mobic overdose include nausea, vomiting, stomach pain, loss of consciousness, drowsiness, headache, cardiac arrest, stomach pain, seizures, little or no urine production and slow breathing.

What should I avoid while taking Mobic?

Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, Mobic may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking Mobic if you drink more than 3 alcoholic beverages a day.

Many over-the-counter cough, cold, allergy and pain medicines contain aspirin or other medicines similar to Mobic (such as ibuprofen, ketoprofen and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of Mobic?

Contact your doctor if you experience bloody, black or tarry stools, blood in your vomit; swelling or rapid weight gain (fluid retention); unusual fatigue or weakness; yellowing of the skin or eyes; excessive itching; flu-like symptoms; or abdominal pain or tenderness. These symptoms could indicate serious side effects.

If you experience any of the following serious side effects, stop taking Mobic and seek medical treatment or contact your doctor immediately:

an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue or face; or hives);

muscle cramps, numbness or tingling;

ulcers (open sores) in the mouth;

seizures;

decreased hearing or ringing in the ears; or

abdominal cramping, heartburn or indigestion.

Other, less serious side effects may be more likely to occur. Continue to take Mobic and talk to your doctor if you experience

dizziness or headache;

nausea, diarrhea, or constipation;

depression;

fatigue or weakness;

dry mouth; or

irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Mobic?

Before taking Mobic, tell your doctor if you are taking any of the following drugs:

aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others) and magnesium salicylate (Doan's, others);

another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), naproxen (Aleve, Anaprox, Naprosyn, Naprelan, others), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril) or tolmetin (Tolectin);

an over-the-counter cough, cold, allergy or pain medicine that contains aspirin, ibuprofen, Mobic or ketoprofen;

a diuretic such as furosemide (Lasix), bumetanide (Bumex), ethacrynic acid (Edecrin), torsemide (Demadex), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn) and others;

an anticoagulant (blood thinner) such as warfarin (Coumadin); or

lithium (Eskalith, Lithobid, others); or

You may not be able to take Mobic or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with Mobic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals and herbal products.