How to Use

To guarantee the safe use of Letrozole, let your doctor know if you are allergic to the drug and if you have not completely gone through menopause. Your doctor should also be informed of your medical history especially on conditions relating to:

• High cholesterol
• Liver disease
• Osteoporosis, osteopenia
• If you have taken tamoxifen

Letrozole should be used with a prescription. The dose is taken once a day or once every other day. Follow the directions of the doctor precisely to avoid complications or poor results. Don’t take the medicine in smaller or larger doses than directed.

You can take Letrozole with food or on an empty stomach. Frequent blood tests will be needed to determine if the drug is causing harm to your body. Your doctor may also request to check your bone mineral density regularly.

FDA Pregnancy Classification

Letrozole can cause harm to an unborn baby. You should not use it while pregnant or before you completely go through menopause. Your doctor should be informed immediately if you become pregnant. It is unknown if Letrozole can be passed into breast milk or if it can cause harm to a breastfeeding baby. You should also let your doctor know if you are nursing a baby.

Missed Dose

Take the missed dose when you remember. Skip the dose if it is almost time for the next dose. Never take extra medicine to compensate for the missed dose. To achieve the best results, make the effort of taking the dose at the same time each day or every other day.

Storage

Store at room temperature and away from heat and moisture.

Side Effects

Serious

• Allergic reactions (difficulty breathing, hives, swelling of the face, tongue, lips or throat)

Common

• Increased sweating
• Dizziness, weakness, drowsiness, tired feeling
• Flushing (redness, tingly feeling or warmth)
• Headache
• Muscle, bone or joint pain
• Hot flashes; warmth in the face or chest
• Weight gain
• Swelling

Safety

Letrozole is not indicated for use in women who have not gone through complete menopause. This is because the drug can cause harm to an unborn baby or even cause severe birth defects. Do not use Letrozole while pregnant.

Letrozole may impair your reactions and thinking. Avoid driving and handling tasks that require undivided attention.

The active ingredients can be passed into body fluids such as vomit, vaginal fluid and urine. Caregivers should use rubber gloves when cleaning body fluids or handling the contaminated laundry or trash. Pregnant women should not handle the body fluids.

Interactions

Letrozole has interactions with 90 drugs.